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    • Nam Nguyen

      By Nam Nguyen
      Resistin<=> A new hormone (see HORMONES) recently identi?ed by researchers in the United States. It links OBESITY to type 2 diabetes (see DIABETES MELLITUS – Non-insulin dependent diabetes mellitus (NIDDM)) and its name is based on its action – namely, resistance to INSULIN. This resistance is a hallmark of this type of diabetes and is manifested throughout the body. THIAZOLIDINEDIONE DRUGS, a new class of antidiabetic drugs that lower insulin resistance, are mediated by receptors which are abundant in fat cells, and the researchers claim to have identi?ed a fat-cell PROTEIN that may be responsible for this and which they believe to be a hormone; it was also found in high concentrations in diabetic mice.